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Testosterone levels fall after marriage

Testosterone levels fall sharply in men after they marry, Danish researchers have claimed.

A team at Rigshospitalet in Copenhagen examined data relating to 1113 Danish men aged between 30 and 60 over a ten year period. It had been gathered as part of a long-term health study. Levels of testosterone and related reproductive hormones were compared with changes in the men’s lifestyles and marital status.

Levels of the male hormone underwent an “an accelerated age-related decline” in those men who married during the study period. By contrast, testosterone levels in men who divorced experienced an “attenuated [weakened or reduced] age-related decline”.

Study co-author Anna-Maria Andersson said:

“Testosterone plays a role in everything that defines a man. It’s quite amusing and it’s a good picture of how much our hormones are impacted by how we live. The body acclimatises to the situation we find ourselves in.”

The team suggested that increased levels of the social bonding hormone oxytocin following marriage and the birth of children could account for the fall in testosterone.

Andersson explained:

“It is of course necessary for the man to defend his wife and children, so you still need testosterone. But it is also necessary to modify your behaviour towards those you need to protect, and it’s important to relate to your family and create social bonds.”

Exposure to female pheromones (biological chemicals that affect behaviour) may also play a role in reducing testosterone levels.

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Of course, female sexuality is a merchandise. That's the nature of human reality. And it's the essence of culture. Because the alternative would be that men appropriate female sexuality by violence. And that's less pretty.

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The Human Vivisections of Herophilus

Ancient physician Herophilus is considered the father of anatomy. And while he made significant discoveries during his practice, it's how he learned about internal workings of the human body that lands him on this list.

Herophilus practiced medicine in Alexandria, Egypt, and during the reign of the first two Ptolemaio Pharoahs was allowed, at least for about 30 to 40 years, to dissect human bodies, which he did, publicly, along with contemporary Greek physician and anatomist Erasistratus. Under Ptolemy I and Ptolemy II, criminals could be sentenced to dissection and vivisection as punishment, and it's said the father of anatomy not only dissected the dead but also performed vivisection on an estimated 600 living prisoners [source: Elhadi].

Herophilus made great strides in the study of human anatomy — especially the brain, eyes, liver, circulatory system, nervous system and reproductive system, during a time in history when dissecting human cadavers was considered an act of desecration of the body (there were no autopsies conducted on the dead, although mummification was popular in Egypt at the time). And, like today, performing vivisection on living bodies was considered butchery.

There is no denying that involving living, breathing humans in medical studies have produced some invaluable results, but there's that one medical saying most of us know, even if we're not in a medical field: first do no harm (or, if you're fancy, primum non nocere).

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Every man easily can become a Muslim. Just have to say the Shahada before some witnesses. And here we go.

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Not Science Fiction: A Brain In A Box To Let People Live On After Death

Scientists believe it may be possible in the future for human brains to survive death in robotic bodies. but would we want to?

I recently had the unusual experience of seeing three renowned scientists discuss whether it’s possible to remove a human brain from a body, put it in a tank, and give it a robotic body. This wasn’t some bizarre late-night bar discussion: The conversation was a serious talk conducted on stage at a conference at New York’s Lincoln Center. The University of Southern California’s Theodore Berger, Duke University’s Mikhail Lebedev, and Alexander Kaplan of Moscow University, all believe it’s possible for the brain to survive body-death inside a cybernetic shell.

In their panel at the Global Future 2045 conference, the trio discussed a future that sounds like a combination of Eternal Sunshine of the Spotless Mind, the recent mouse inception, and Krang, the brain-in-a-box villain of Teenage Mutant Ninja Turtles. The talk, which took place in a mixture of Russian and English, focused on making it possible in our lifetime to conduct brain transplants, harvesting human parts from the body for cybernetic integration, and making self-aware brains comfortable in their new robot homes. It was just another Saturday afternoon, in other words.

Notably absent from the conversation was what the quality of life would be for human brains harvested into robotic bodies. Although all three researchers come from impeccable neurology backgrounds, the talk centered on mostly whether it would be possible to make the technology work. Whether it would be wise, or what the experience would be like for both patients and loved ones, wasn’t discussed as much.

The three researchers believe brain transplants are possible because the human brain is the last organ in the body to cease function after death. Because the death process includes a short window where the brain functions without support from other organs, Berger, Kaplan, and Lebedev all believe there is precedent to have the human brain functioning indefinitely in a non-human carrier–as long as the appropriate support system is there for the brain. They also stress the fact that nerve cells age slowly compared to other organs.

This brain-in-a-robot would be supported by biological blood substitutes (with “the necessary hormonal-biochemical and energetic substrate”), multi-channel brain-computer interfaces with two-way information exchange, neural prostheses, artificially regrown human organs, and other biotech tools that we can’t even imagine. Because there is no precedent for the human brain surviving and functioning outside of a human body, degrees of consciousness, intelligence, comprehension, and a million other existential quandaries that would or wouldn’t exist in a robo-brain simply aren’t evaluated. The data points aren’t there for us to understand, even if it’s possible to transplant a human brain into a robot, what it’s like to be a human brain transplanted into a robot.

There are even interim holding facilities where living human brains could hypothetically be stored before transplantation.

While their roundtable discussion admittedly sounded like a master’s exercise in strange science, the kicker is that all three are engaged in preliminary efforts to make this happen. Last year, at the resolutely mainstream MIT Media Lab, I saw Dr. Berger speak about hacking the memories of rats. Berger’s lab at USC is actively working on prosthetic brain implants that both falsify memories and stimulate brain function in damaged neurons. The lab’s work recently received media attention when it successfully generated new memories in a rat that had its hippocampus chemically disabled. In literature, Berger emphasizes his technology’s potential for treating Alzheimer’s and dementia through the possibility of “building spare parts for the brain;” on-stage in New York, he said it could also lead in the future to full-on brain transplants.

This would work in tandem with Kaplan’s and Lebedev’s specialties. The two Russian scientists research brain-computer interfaces (BCIs)–plug-in interfaces which meld the human brain and nervous system to computer operating systems. While BCIs are most commonly found in toys that read brainwaves to detect stress or concentration, they have revolutionary potential to change the lives of stroke victims and the disabled.

When combined, brain prosthetics and brain-computer interfaces could lead to brain transplants decades from now. Would you want to spend decades or even a century living inside a robotic body at the mercy of a software interface to navigate the world? We’re just beginning to grasp the ethical, philosophical, and scientific implications. But with the right amount of funding, research, and cooperation, it’s entirely possible.

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Erectile dysfunction is mostly a vascular disease. An Egyptian professor found the solution. Botox injections into the penis, once every six month. A simple procedure that even nurses can handle.

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Arthur Gary Bishop

Summary:

Arthur Gary Bishop went from being a honor student, Eagle Scout and teenage missionary to an obsessed pedophile and child killer that he later attributed to pornography that he was to exposed to while growing up.

Personal Information:

Born - 1951 Birthplace - Hinckley, UT Died - June 10, 1988 Location of Death - Utah State Prison Cause of Death - Execution - Lethal Injection General Information:

Gender - Male Religion - Mormon Ethnicity - White Education - Stevens-Henager College Occupation - Accounting Crime Chronology:

1978 - Excommunicated from the Mormon Church 1978 - Embezzlement 1984 - Murder 1984 - five counts - convicted 1984 - Kidnapping 1984 - five counts - convicted 1984 - Sexual Abuse 1984 - Sexual Abuse of a Minor Profile:

Gary Bishop molested children for many years without being caught. At some point his crimes advanced to murder, which he discovered also fed his sick needs. Bishop killed five young boys from 1979 until his capture in 1983. To try to control his impulses he would perform his abuse on puppies, but that failed.

After confessing to his crimes he was tried and sentenced to death. In preparation for his execution by lethal injection, he read the Book of Mormon repeatedly and shielded himself from the profanity spoken by the other inmates by wearing headphones.

In the final hours prior to his execution he fasted and prayed. Arthur Gary Bishiop was executed by lethal injection by the state of Utah on June 10, 1988. He was 37 years old.

Known Victims:

Alonzo Daniels Age four. Murdered after being kidnapped from his families apartment complex courtyard.

Kim Peterson Age 11.

Murdered after going to Bishop's home to sell him his roller skates.

Danny Davis Age four. Murdered after being kidnapped at a grocery store.

Troy Ward Age six. Murdered after being kidnapped on his birthday from a park near his home.

Graeme Cunningham Age 13. Murdered after he vanished from his neighborhood.

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As a man, instead of lamenting the Islamization of Europe, put yourself in the camp of the victors. Any man can become a Muslim by just uttering the Shahada. A matter of 5 minutes.

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UAE has strict rules against prostitution

Khaleej Times

Reacting to media reports about a Russian hooker in Dubai earning thousands of dollars working as a prostitute, the Dubai Police have confirmed that prostitution and adultery are illegal and punishable crimes, and that sex workers will be brought to justice and deported if caught by police.

Must read: Man, woman on trial in UAE for trafficking, running brothel

The Sun newspaper reported, recently, that the woman makes about Dh500,000 a year. According to the newspaper, the woman who has been working in prostitution for the last eight years, deals with about five customers per day. However, it is not clear if she has spent all the eight years in the UAE.

Shocking: Asian man sells Dubai maid into prostitution for Dh4,000

The Sun reported that the 25-year-old Russian recently featured in a high court case where she was said to have been paid by an investment banking company to befriend a Libyan contact. She is said to have taken the client to a hotel in Dubai.

Unbelievable:Two Sharjah men force wives into prostitution for expenses

According to The Sun, the woman used to advertise as: "I have sexy shapes and great appetite for naughty games."

Commenting on the report, a police official said that the Dubai Police will not turn a blind-eye to such behaviour and that there are strict laws banning women from even wearing indecent cloths or committing any kind of immoral activities.

Crime: 3 men steal money from prostitute, court hears

He clarified that such odd incidents happen in every country and that such activities are against the UAE's tradition and culture.

He added that the Dubai Police conduct raids on a daily basis and arrest all those involved in prostitution. They are then brought to justice and deported.

The police also blocks websites with indecent photographs of women and interact with such kind of women in order to trap them after getting necessary permission from legal authorities.

The official called up on the public to inform the police if they came across any such advertisements or illegal activities.

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The Spanish masturbation guru Fran Sanchez is on the wrong path. Just imagine him handling his sexuality alone on his couch or in the toilet. A picture of pity, he is.

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It is the secret dream of every Swedish or German woman to marry a black men, or at least have sex with a black man. Every smart young African man should migrate to Europe. Free money, nice house, good sex!

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Effects of Long-term Treatment of Butea superba on Sperm Motility and Concentration

Abstract

Butea superba has been used to enhance sexual performance in men with unknown long-term effects on spermatozoa. This study aimed to investigate effects of chronic treatment of B. superba on sperm motility and concentration in rats and mice in correlation with testicular damage. Adult male rats and mice were orally administered distilled water or B. superba alcoholic extract (0.01, 0.1 or 1.0 mg/kg BW/day) for 6 months. At the end of the treatment the animals were sacrificed and the spermatozoa recovered from the distal cauda epididymis were analyzed for sperm concentration and motility in vitro. The testes were processed for histological examination. The results show that long-term treatment with B. superba extract significantly increased the sperm concentration and delayed the decreased motility with time. None of signs of sperm anomalies and testicular damages were observed. This suggests that chronic use of B. superba increases the number of sperm, prolongs sperm motility in vitro while produces no changes on sperm morphology. Therefore, chronic use of B. superba alcoholic extract may be useful in fertilization.

Introduction

Butea superba, known as "Kwaao Khruea Daeng" in Thai, has been used for physical and mental strength and for preventing age-related health problems. Thai traditional medicine uses B. superba as a rejuvenating agent and to increase sexual performance in men (Suntara, 1931). The plant preparation appears to improve an erectile function in patients with erectile dysfunction (ED) without any apparent toxicities (Cherdshewasart and Nimsakul, 2003). Fertilization in vivo requires adequate numbers of spermatozoa to be ejaculated with normal morphology and motility (Adamopoulos et al., 1996). Since spermatogenesis involves a complex process of cellular development, impairment in any of the development stages may lead to a reduction in the fertility. Long-term utilization of any sexual enhancers may affect the amount of and/or characteristics of spermatozoa resulting in altered fertilization capability. Therefore, this study aimed to investigate effects of chronic treatment of B. superba alcoholic extract on sperm motility and concentration in correlation to testicular damage in rats and mice.

Materials and Methods

Extract preparation

B. superba tuber roots were collected from Phrae, Thailand, and identified by Associate Professor Yuttana Smitasiri, School of Science, Mae Fah Luang University, Thailand. The roots were washed and air-dried at room temperature. The root cores were separated and sliced into small and thin pieces. Then they were dried in a hot air oven at 50o C and grinded into fine powder. The powder was extracted 3 times with ethanol at 1:4 ratio w/v and stirred overnight at room temperature. The ethanolic extract was evaporated under reduced pressure at 45o C using a rotary evaporator. The extract was dissolved in distilled water before used. Animals Male Sprague-Dawley rats (8 wks) and ICR mice (8 wks) were obtained from the National Laboratory Animal Center, Mahidol University, Nakornpathom, Thailand. They were housed under a 12:12-hour light-dark cycle and maintained at 24 + 1o C.

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Extract treatment

Groups of 6 animals were randomly divided into four groups: one control and three different treatment groups. The control rats and mice were orally administered distilled water daily for 6 months. The treatment groups received alcoholic extract of B. superba at the doses of 0.1, 1.0 or 10.0 mg/kg BW daily for 6 months. Preparation of culture drop Motility test was performed in the tissue culture medium 199 (TCM199) modified with Earle's salt with L-glutamine (Life Technologies, USA) and supplemented with 3 mg/ml bovine serum albumin (Sigma, USA). Sperm motility evaluation was performed in a 100-µl droplet under 10 ml paraffin oil in a 60-mm petri dish (Nunclon, Denmark) and equilibrated overnight in high humidified atmosphere at 5% carbon dioxide (CO2) in air before further analysis.

Sperm motility assay

Sperm motility was assessed by the method of Bavister and Andrews (Bavister and Andrews, 1988). The distal cauda epididymis was dissected out and placed in 2 ml of equilibrated medium in a 35-mm tissue culture dish. A needle was employed to release the spermatozoa from the cauda epididymis into the medium. The spermatozoa were allowed to swim out into the medium for 3 min in the CO2 incubator at 37o C. Sperm concentrations were then determined. The medium was added to the culture drop for sperm motility assay providing a final concentration of 2 x 106 spermatozoa/ml. The tissue culture dish was placed under an inverted microscope (Nikon, Japan) and an observation was performed at a magnification of 20X within 1 min. The motility of sperm was observed at various time intervals up to 6 hrs.

Sperm count and morphology

Testicular histopathology The testis was dissected out, cut into small slices, and fixed in 10% formaldehyde buffer for 24 hrs. The tissues were washed free of 10% formaldehyde and stored in 70% alcohol until being embedded. The tissues were dehydrated in alcohol series and embedded in paraffin. Tissue sections of 5 µm thickness were prepared and placed on glass slides. The sections were stained with hematoxylin and eosin and mounted in mounting medium. The slides were examined under the light microscope. For each testis several cross sections composing of 20-50 tubule sections were examined for signs of interstitial edema, seminiferous tubule degeneration, and congestion.

Statistical analysis

Statistical analysis was performed using one way analysis of variance (ANOVA). If a significance was found, differences among individual group means were tested by the least significant difference (LSD) test. Values were considered statistically significant at P<0.05. The cauda epididymis was cut and weighed. A cell suspension was prepared by macerating the cauda in 1.0 ml of 0.85% saline. The cell suspension was kept for 24 hrs at 4o C. The suspension was then filtered through a double gauze layer and an aliquot of the sample was used for sperm count in a Neubauer hemocytometer. An aliquot of the epididymal sperm suspension was smeared and stained with hematoxylin and eosin and then examined under a light microscope (CH-2, Olympus, Japan) at magnification of 100X. The head and tail abnormalities (200 sperms per animal) were recorded.

Results

Effect of B. superba on sperm motility Motility of the sperms from the control rats and mice at time zero were about 90% (Figures 1 and 2). The movement gradually declined with time and reduced to 70% at 6 hrs in both species. Long-term treatment of the animals with B. superba alcoholic extracts at the doses of 0.01, 0.1 or 1.0 mg/kg/day significantly delayed the reduction of the sperm motility compared to the control group. The motility of sperms from the treated animals remained over 75% at the sixth hour after being investigated. However, at the time zero, the extract-treated groups revealed no difference in motility compared to the control group.

Discussion and Conclusion

Sperm motility has been considered as one of the most important predictors of fertility. Several reports have demonstrated the correlation of motion parameters with fertilization rates (Check et al., 1990; Liu et al., 1991). Adenosine triphosphate (ATP) is the main energy source of the sperm motility. A reduced ATP production and/or reduced ATP levels via ATPase hydrolysis result in an insufficient energy and poor sperm motility. This study shows that B. superba prolonged the sperm motility via unknown mechanisms. It is possible that B. superba may increase the ATP production and/or utilization. In addition, it cannot be ruled out that the plant may act on the nitric oxide (NO)-cyclic adenosine monophosphate (cAMP) pathway. A number of studies have reported involvements of the NO and cAMP in the sperm motility. A nitric oxide synthase (NOS) inhibitor (NG -nitro-L-arginine methyl ester) (Lewis et al., 1996) and a NO scavenger (methylene blue) (Donnelly et al., 1996) were reported to inhibit movement of human spermatozoa. Sildenafil, an inhibitor of phosphodiesterase V, increases the velocity and amplitude in human spermatozoa (Lefievre et al., 2000). Sildenafil also dose-dependently increases cAMP production in the spermatozoa. Human spermatozoa subjected to capacitating conditions increase their endogenous NO synthesis and their intracellular cAMP content. The cAMP synthesis is increased by NO releasing compounds and decreased by NOS inhibitors (Belen Herrero et al., 2000). These studies suggest an involvement of the NO and cAMP in the movement of the spermatozoa. B. superba has been reported to inhibit phosphodiesterase activity in vitro (Roengsumran et al., 2000). Therefore, it is possible that B. superba may also prolong the sperm motility by increasing the cAMP production. However, further studies are required to confirm the proposed mechanisms of action of B. superba.

An assessment of a sperm motility loss over time is normally used as a quality control of an in vitro culture medium used in clinical analysis of Assisted Reproductive Technology (ART). Some laboratories employ sperm survival or stress tests to enhance the predictability of the in vitro fertilization rate (Alvarez et al., 1996; Coccia et al., 1997). Therefore, the motility results from this study are valid for further use in clinical study design of B. superba. The prolonged sperm motility in the culture medium by B. superba extract indicates that B. superba may be useful in infertile men. The number of spermatozoa was increased by B. superba extract. This may be caused by β-sitosterol component in B. superba. The enzymes in the testis convert β-sitosterol to pregnenolone, an important substrate of testosterone synthesis (Subbiah & Kursis, 1975). The testosterone activates the release of gonadotropin-releasing hormone (GnRH) from hypothalamus. The follicle-stimulating hormone (FSH) and luteinizing hormone (LH) released by the GnRH induce the spermatogenesis and growth of spermatozoa.

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Islamic State strategists are amateurs. They haven't recognized the power of arson. Setting Third World cities like Kairo or Lagos on fire will drive millions of refugees to Europe, and finally islamize it.

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Sexual Behavior in Dutch and Belgian Children as Observed by Their Mothers

Abstract

Mothers' observations (N = 670) of child sexual behavior have been collected using an adapted version of the Child Sexual Behavior Inventory as developed by Friedrich et al. (1991). The ages of the boys (N = 351) and girls (N = 319) observed range from 0 to 11 years. The results show that there is a lot of variance in the frequency with which specific sexual behaviors are observed. The occurrence of specific behaviors varies with age. While some behaviors are observed more frequently as the child gets older, others are observed less frequently. Boys and girls only differ in a few behaviors. The finding that the behavioral items form an internally consistent scale suggests that there is a general tendency to show sexually related behaviors, which is more or less strongly present in children, which might be a precursor of differential levels of sexual desires in adults.

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Feminism in Europe makes second-generation male Muslim immigrants suicide bombers. Only the patriarchy as a social and political system can achieve justice.

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